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Fish Medications

The immune systems in fish can weaken from stress, environmental factors and poor nutrition, making them susceptible to common fish diseases. You'll find all the necessary treatments for these bacterial and parasitic diseases below. The majority of these diseases can be prevented with routine maintenance such as partial water changes, water testing, and of course population control.

Fish Medications
Aqua Meds Fish Medications

Keeping your koi and goldfish happy and healthy offering a full product line of liquid and dry treatments.

Hikari Fish Medications

A new approach to medicating your pond or holding tank, highly effective products with recovery-inducing benefits.

Microbe-Lift Fish Medications

Reduce the potential for common diseases and treat current with Microbe-Lift's complete product line of fish health treatments.

API PondCare Fish Medications

All natural anti-bacterial and anti-fungal remedies for koi and goldfish.

Pond Salt

A general fish tonic made from evaporated sea water. Improves gill function, protects against nitrite toxicity & reduces stress by helping to maintain a natural balance of electrolytes in the body fluids of pond fish.

SuperNatural FishShield

Fish are expensive, so protect them with FishShield fish treatment. FishShield helps keep materials out of the pond that cause fish health to deteriorate.

All Fish Medications

The immune systems in fish can weaken from stress, environmental factors and poor nutrition, making them susceptible to common fish diseases. You can find all the necessary treatments for these bacterial and parasitic diseases here.

Our Most Popular Fish Medications

Aqua Prazi, 100% Pure Praziquantel, No Fillers, No added Medications!

Aqua Prazi is one of the safest most effective medications on the market for treating deadly flukes; it does not stress your pond fish or set back your filter. Plus, Aqua Prazi is an excellent treatment for tape worms in goldfish, koi and pond fish. We suggest treating with Aqua Prazi every spring to get your pond fish off to a great season and again in the fall before their long winter's nap. Plus, treat all your new fish, very important!

  • No temperature restrictions
  • Contains no fillers or additional medications
  • Does not stress koi or set back your filter
  • The safest pond treatment for fluke parasites

Aqua Meds Aqua Prazi Application Rates
Start with a 10% pond water change or more. Remove carbon from your pond filter, DO NOT shut off filter. Shut off U.V. light only, for 24 to 48 hours, do not shut off water pump to U.V. Shut off protein skimmer.
One gram of Aqua Prazi treats 100 gallons, 10 grams treats 1,000 gallons. Add Aqua Prazi to one quart of pond water and shake vigorously for 3 to 5 minutes. Add this mixture to a 4 to 5 gallon bucket of pond water and mix well.
Two treatments work the best. The first treatment will kill all the live flukes. The second treatment, 3 days later will kill all the young as they hatch from their eggs.
No water changes for seven days from the first treatment.
Distribute the mixture around the edge of the koi pond or directly into the skimmer or filter outlet to achieve maximum distribution in the pond water. Do not use any other koi pond medications or treatments. FDA prohibits the use of this product on fish used for human consumption.
Note: One level tablespoon of Aqua Prazi for fish will treat approximately 500 gallons. Aqua Prazi is an excellent koi medication for treating flukes.
Aqua Meds Aqua Prazi

Aqua Meds Aqua Prazi

  Icons SKU Size Treats (up to)
78037
25 grams
2,500 gallons
78038
50 grams
5,000 gallons
78036
100 grams
10,000 gallons

Ich-X utilizes the most widely respected formulation for the treatment of ich, with a less toxic form of malachite green.

  • Treats Ich
  • Treats Cryptocaryonaisis
  • Treats Trichodiniasis
  • Treats Velvet (Gold Dust)
  • Treats Saprolegniasis
  • Uses A Less Harsh Form Of Malachite Green
Pond Solutions Ich-X Application Rates
Add 1 tsp. per 20 gallons of water
For best results - Always treat in a separate quarantine/treatment tank. Remove activated carbon from filters and clean or replace mechanical filtration media but do not stop filtration. Perform at least a 1/3 water change before treatment. Repeat treatments at least every 24 hours, but no more often than every 8 hours.
Immediate 50% or larger water change should be done if stress is observed among fish
Hikari Pond Solutions Ich-X

Hikari Pond Solutions Ich-X

  Icons SKU Size Treats (up to)
73214
4 Ounces
240 gallons
73336
16 Ounces
4,800 gallons
73338
1 gallon
38,400 gallons

Formulated with Malachite Green & Formalin. Use for disease caused by Ichthyophithirius (Ich), Chilodonella, Costia, Oodinium, Trichodina and fungal infections.

Microbe-Lift BSDT is the #1 treatment when you do not know what is bugging your fish, a preeminent broad spectrum malachite green and formalin treatment. The only malachite green and formalin treatment that can be used in water temperatures as low as 50°F, thus allowing treatment in early Spring and late Fall. 

Malachite green and formalin are two drugs that are more effective and less toxic in combination than when used individually. This is the definition of synergism. What makes Microbe-Lift BSDT the preeminent product in this field is the fact that it is formulated with malachite green chloride, instead of the more toxic oxalate salt. As with any malachite green and formalin treatment, do NOT use with other medications. Not to be used with salt over 0.15% salinity; at 0.15% salinity, monitor carefully and provide high aeration.

Microbe-Lift Broad Spectrum Disease Dosage
Pond Size (gallons) Dosage
Any Add 3.5 oz. per 1,000 gallons of water
Prior to initial use and each of the 3 applications, at least a 20% water change should be made. A nearly total water change (>90%) will greatly improve effectiveness. Carbon Filtration must be removed and UV's turned off during treatment. You do not have to bypass your bio-filter. Do not overdose.
Treat once a day for 3 consecutive days. You do not need to do a water change after you finish the third treatment. After treatment, it is recommended to start using Microbe-Lift Sabbactisun and Parazoryne - this is a 10 day treatment to expel any parasites, bacteria, fungal, etc. and assists healing. 

Cannot ship when temperatures are freezing

Microbe-Lift Broad Spectrum Disease Treatment

Microbe-Lift Broad Spectrum Disease Treatment

  SKU Size Treats (up to)
46336
16 Ounces
4,800 gallons
46338
32 Ounces
9,600 gallons
46340
1 gal
38,400 gallons

Antibacterial Remedy for Koi & Goldfish

API Pond Melafix acts as an all-natural, antibacterial remedy for koi and goldfish diseases, including eye cloud, mouth fungus, fin & tail rot, damaged fins, ulcers, and open wounds. Use if you notice these symptoms among fish in your pond, or when adding new fish. Pond Melafix is safe for snails and other invertebrates, and will not harm aquatic plants, affect pH, or adversely affect your pond’s natural biological filter. Can be used with Pimafix.

Pond Care Mela Fix Dosage
For Recent Wounds, Fin Damage, or Infection: Add 1 tsp. for every 50 gallons of pond water.
When treating an advanced or chronic infection: Add 2 tsp. for every 50 gallons of pond water.
Dose daily for 7 days. Treatment may be continued if necessary.
When adding new fish, or netting and handling fish: Add 1 tsp. for every 50 gallons of pond water, once per day for 3 days.
Foaming may occur during the treatment. When exposed to elevated temperatures, this product may turn cloudy in the bottle; this does not affect the activity of the product.

WARNING: This product can expose you to chemicals including beta-Myrcene, which is known to the State of California to cause cancer. For more information go to www.P65Warnings.ca.gov.

API Pond Melafix

API Pond Melafix

  Icons SKU Size Treats (up to)
02176
16 Ounces
4,800 gallons
32176
64 Ounces
19,200 gallons

A unique, natural fish parasite repellant. Proven effective against bacterial dropsy, fungus and ulcers in fish. Expels pathogens from fish and stimulates its immune system response. Can speed up damaged tissue regeneration. Sabbactisun is made with plant and herbal extracts making it environmentally friendly. Supports immune system, driving off the excess parasites. Product is harmless to all nitrifying filter bacteria and aquatic plants.

  • 100% natural plant and herbal product
  • Non-toxic to animals and plants
  • Can be used during feeding
  • Does not adversely affect either nitrifying filter bacteria or beneficial bacteria 
  • Stimulates the immune system
  • Sabbactisun and Parazoryne can be used 12 hours apart
Microbe-Lift Sabbactisun Dosage
Add 1 teaspoon per 125 gallons of water
Use daily for a minimum of 10 days. For best results, use when water temperature is at least 71°F (22°C)

Cannot ship when temperatures are freezing

Microbe-Lift Sabbactisun

Microbe-Lift Sabbactisun

  SKU Size Treats (up to)
21074
16 Ounces
1,182 gal for 10 days
21075
32 Ounces
2,365 gal for 10 days
21076
1 Gal
9,462 gal for 10 days
21077
2.5 Gal
23,654 gal for 10 days

Reduce DEADLY Water Borne Bacteria in your pond.

Aqua MedZyme Dry reduces the deadly bacteria in your pond by starving them to death. These deadly bacteria live in every koi fish pond, causing life threatening bacterial infections attacking koi when they are stressed, causing thousands of fish deaths each year. Aqua MedZyme Dry consumes the same food that Aeromonas, Pseudsomonas live on and starves them to numbers so low they become harmless to your koi & pond fish.

  • Renders deadly ulcer causing Aeromonas, Pseudomonas harmless to your fish
  • Treats pond water as low as 40°F 
  • Great for early spring & late fall treatments
  • Can be stored at room temperature
  • Does NOT contain chemicals, antibiotics or medications
  • Safe for filters, plants, pets and wildlife
AquaMeds MedZyme Dry Concentrate Application Rates
Pond Size Dosage
100-2,500 gallons First Dose 1 Tbsp. (scoop) every three days for three treatments, then 1 Tbsp. each week for two weeks
Maintenance ONE HALF tablespoon every other week
2,501-5,000 gallons First Dose 1 Tbsp. (scoop) every three days for three treatments, then 1 Tbsp. each week for two weeks
5,001-10,000 gallons First Dose Double the dosage.
Maintenance ONE tablespoon every other week
Aqua Meds MedZyme DC Dry Concentrate

Aqua Meds MedZyme DC Dry Concentrate

  Icons SKU Size Treats (up to)
78046
1 lb
125,000 gallons
78047
2 lbs
250,000 gallons
78048
24 lbs
-
Treatment for lice and anchor worms

Microbe-Lift Lice & Anchor Worm is the most effective treatment for diseases of fish caused by lice and anchor worms. When used as directed, it will not harm biological filtration and may be used on scaleless fish. Can be used in any water temperatures above 40º F. Should be stored in the original container above 40ºF and under 100ºF. Do not store in direct sunlight and do not allow to freeze.

This product is intended for use with all ornamental pond fish. Not for use with fish or aquatic invertebrates intended for human consumption. Not for human or veterinary use.

Microbe-Lift Lice & Anchor Worm Dosage
Add 1 ounce per 300 gallons of water (1 time weekly for 3 weeks)
Prior to the initial use, a partial water change of 20% is recommended. This removes pollutants for disease-causing organisms and will reduce the number of water-borne pathogens.
For best results, perform three treatments one week apart with water changes prior to each re-treatment.

Contraindications: Safe for use on all ornamental pond fish, reptiles, amphibians and mollusks. Must NOT be used where crayfish and other crustaceans are being cultured. Keep out of reach of children. Shake well before use.

Cannot ship when temperatures are freezing

Microbe-Lift Lice & Anchor Worm

Microbe-Lift Lice & Anchor Worm

  SKU Size Treats (up to)
20417
16 Ounces
4,800 gallons
20418
32 Ounces
9,600 gallons
20419
1 gallon
38,400 gallons

Ready-to-use, liquid concentrate that was developed to offer the hobbyist an effective way to control unwanted parasites in their pond, freshwater or marine aquarium. Extremely safe and highly effective this revolutionary product offers you rapid control yet will not negatively impact your biological filtration.

  • Treats flukes, tapeworms, flatworms, turbellarians
  • Extremely Safe and highly effeective
  • Will not negatively impact biological filtration
Pond Solutions PraziPro Application Rates
For treatment of prazi-quantel-susceptible disease conditions
Start treatment with a large water change or start with new water. Any water used should first be conditioned with ULTIMATE or a combination of ClorAm-x & Stress-X to remove ammonia, chlorine and chloramines.
Do not stop filtration, but remove activated carbon, stop protein skimming & turn off U.V.
Add 1 oz. per 120 gallons of pond water.
Distribute the proper amount around the edge of the pond or directly into the filter box to achieve the best overall distribution.
A single treatment lasting 5-7 days is normally sufficient. Retreat as necessary, but no more than once every 3-5 days.
May be used as a preventative, at the standard dosage, when disease is likely.
May cause noticeable temporary foaming
Hikari Pond Solutions PraziPro

Hikari Pond Solutions PraziPro

  Icons SKU Size Treats (up to)
73254
4 Ounces
480 gallons
73256
16 Ounces
1,920 gallons
73258
1 gal
15,360 gallons

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